Little Leakers
Lymphatic News
LFR news Fall2007/Winter2008

Congressional Support for Lymphatics
The FY 2008 Congressional Appropriations Committee Reports
for both the Senate and House urge the National Institute of
to continue and expand its efforts to relating to lymphatic
research and lymphatic health.

"National Heart, Lung, and Blood:  The Committee commends
the NHLBI for its leadership role in lymphatic research and
strongly encourages amplified continuation of these efforts in
concert with ... other relevant ICs.  In addition, the Committee
urges the NHLBI,s Lung Division to engage in lymphatic
research initiatives, with particular attention to congenital
lymphatic malformation-induced pulmonary dysfunction.

"National Institute for Diabetes and Digestive and Kidney
 The NIDDK is urged to study the medabolic link
between lymphatic function and obesity, dyslipedema and
diabetes.  In study protein-losing enteropathy, a
life-threatening complication associated with numerous
syndromes involving congenital lymphatic malformations.

To read the reports in full (Departments of Labor, HHS, and
Education, and Related Agencies Appropriations Bill, 2008:
Senate Report 110-107 and House Report 110-231)
visit and/or for relevant sections visit
LFR news Fall2006/Winter2007

LFR's strategy has been to target a number if NIH (National Institute of
Health) institutes in our effort to gather support.  LFR has received
important congressional encouragement from both the House and
Senate in the language used to allocate appropriations for the NIH
through the Department of Health and Human Services (HHS).  The
House HHS Appropriations Report Language for fiscal year 2007 reads
as follows:  

In light if the transformational impact of lymphatic biology and disease
research, which requires the participation of multiple institutes and
centers, the Committee encourages the Director to give careful
consideration to the development of an initiative for lymphatic biology
and disease under the auspices of the Office of Portfolio Analysis and
Strategic Initiatives (OPASI).  In addition, the Committee encourages the
Director and the Trans-NIH Coordinating  Committee on the lymphatic
research initiatives and awareness across all NIH initiatives and centers.

The Senate showed extensive support for lymphatics, as evidence un the
following Senate HHS Appropriations Report Language for fiscal year

The lymphatic system plays a vital role in the immune system, the
digestive system, and a wide range of diseases, including lymphedema,
asthma, and cancer.  There is growing evidence, for example, that
intervening in the lymphatic system could help reduce the spread of
tumors.  Other research suggests that it contributes to unwanted
inflammation.  Until recently, however, the scientific and medical
professions have not sufficiently recognized its importance.  While
substantial resources have been spent to study the blood circulatory
system, far fewer have been devoted to the lymphatic circulatory system.  
Therefore, the Committee urges the NIH to consider research on the
lymphatic system as an initiative within the newly created OPASI.  In
keeping with OPASI's purpose, such research would address an area of
emerging  scientific opportunity, and it would not focus on a specific
group of diseases, but a broad range.  Furthermore, while a better
understanding of the lymphatic system would benefit numerous Institutes
and Centers, basic research in this area currently falls both within and
between existing IC missions - a situation that contributes to the scientific
neglect of the lymphatic system.  The Committee also urges the NHLBI,
NCI, NIAID and other Institutes and Centers to improve coordination for
lymphatic system research in NIH funding mechanisms such as program
announcements and RFAs.

In addition, specific targeted language was included for the National
Cancer Institute (NCI); National Institute of Allergy and Infectious
Disease (NIAID); National Institute of Diabetes and Digestive and
Kidney Diseases (NIDDK); and National Heart, Lung, and Blood Institute

LFR Participates in Health Symposium Convened  By Senator Clinton

he President of The Lymphatic Research Foundation, Wendy Chaite
was selected by Senator Clinton to take part in a health care forum.  

"As a long-time advocate for improved health care for all Americans, I
applaud the efforts of the Lymphatic Research Foundation to bring this
neglected field of medicine to the attention of governmental
representatives and members of the research community.  I believe that
there needs to be a dramatic improvement in addressing the needs of
the lymphatic disease community."                                       
Hillary Rodham Clinton  U.S. Senator from New York
LFR news Fall2005/Winter2006

Senate Appropriations Committee Report language for 2006 states:

Lymphatic Research:  The lymphatic system is central to the progression
of disease and the maintenance of health, yet scientific and medical
knowledge of this important system is woefully deficient.  While the
Committee is pleased that a Trans-NIH Coordinating Committee on the
Lymphatic System exists to ensure that scientific knowledge and
understanding about this neglected body system will be advanced and
coordinated, adequate efforts and funding are lacking.  Institutes and
Centers are urged to include relevant language addressing basic and
clinical lymphatic system research in all existing and future funding
mechanisms, where such grant applications could be responsive.  The
Trans-NIH Coordinating Committee should be informed of relevant
lymphantic language included within such funding initiatives.

The Committee is encouraged to learn the Trans-NIH Coordinating
Committee on the Lymphatic System, and in particular the NHBLI, is
working with patient advocates ti address the needs of the lymphatic
disease and lymphedema patient communities.
Initiatives such as a national lymphatic disease patient registry/tissue
bank; an NIH partnership funding program; intramural longitudinal
studies; and multidisciplinary centers for research, clinical care, and
medical training are strongly encouraged.